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reduce affinity in a sentence


1) The problem appears to be reduced affinity of the receptor for the toxin.

affinity collocations
2) Vicriviroc had an excellent selectivity for CCR5 receptors over muscarinic and hERG affinity was greatly reduced .

3) Sulfite is with high affinity reduced by sulfite reductase to sulfide with ferredoxin as a reductant.



reduce affinity example sentences

4) This significantly reduces the affinity of Velcade for the proteasome, decreasing its destructive activity toward myeloma cells.

5) In this case, a mutation in the receptor gene results in a receptor that has greatly reduced binding affinity for leptin in the brain.

6) Editing results in reduced affinity for specific G proteins which in turn affects internal signalling via second messengers (Phospholipase C signalling system).

7) Because of this reduced affinity , the activity of glucokinase, under usual physiological conditions, varies substantially according to the concentration of glucose.

8) The antithrombin of subgroup Ia individuals showed a normal affinity for heparin while the antithrombin of subgroup Ib individuals showed a reduced affinity for heparin.

9) GTP reduces hemoglobin oxygen affinity much more than ATP, which is thought to be due to an extra hydrogen bond formed that further stabilizes the tense state.

10) Strychnine binds to an alternate site that reduces the affinity of the glycine receptor for glycine, resulting in convulsions due to lessened inhibition by the glycine.

11) The mutations between the CRP sites reduce the affinity of CytR for deoP2 in vitro



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