genome assembly in a sentence
1) EagleView can handle a large genome assembly of millions of reads.
assembly collocations
2) Hybrid genome assembly can also be accomplished using the Eulerian path approach.
3) The current challenges in genome assembly are related to the limitation of modern sequencing technologies.
genome assembly example sentences
4) However, "de novo" genome assembly by Sanger sequencing is extremely expensive and time consuming.5) Hawkeye has similar memory limitations for large genome assemblies and has no support for viewing genome feature annotations.
6) This release utilises the latest GRCh38 human reference genome assembly , and corresponds to Ensembl release 76.
7) Algorithms specific for this type of hybrid genome assembly have been developed, such as the PacBio corrected Reads algorithm.
8) The upper part shows a genome assembly of 454 sequence reads; the lower part displays an assembly of Illumina reads.
9) Biological and biomedical research has come to rely on accurate and consistent annotation of genes and their products on genome assemblies .
10) EagleView has already proved to be an essential tool in our development of informatics software for genome assembly and polymorphism discovery.
11) Such long read lengths would allow easier "de novo" genome assembly and direct detection of haplotypes, among other applications.
12) Thus, as third generation sequencing technologies improve, rapid and inexpensive "de novo" genome assembly will become a reality.
13) Using the entire read may introduce artifacts in the downstream analyses like genome assembly , snp calling, or gene expression estimation.
14) Using solely second-generation sequencing technologies for genome assembly can miss or lead to the incomplete assembly of important aspects of the genome.
15) Analyzing this short read sequencing data encompasses all of the problems associated with "de novo" genome assembly using short read data.
example sentences with genome assembly
16) Second generation sequencing technologies, while less expensive, are generally unfit for "de novo" genome assembly due to short read lengths.17) These reads must then be put back together like a jigsaw puzzle by aligning the regions that overlap between reads; this process is called "de novo" genome assembly .
18) The computational difficulties that are encountered during genome assembly will also become a concept of the past as computation efficiency and performance increases.
19) Genome assembly is normally done by one of two methods: assembly using a reference genome as a scaffold, or "de novo" assembly.
20) Other challenges have to deal with repetitive sequences that often prevent complete genome assemblies because they occur in many places of the genome.
21) Sequence alignment is also a part of genome assembly , where sequences are aligned to find overlap so that "contigs" (long stretches of sequence) can be formed.
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