azido group in a sentence

1) The 3́hydroxyl group in the deoxyribose ring of thymidine is replaced by an azido group which gives us zidovudine.

2) In zidovudine (AZT; ATC: ) the 3'-hydroxyl group has been replaced by an azido group, in Stavudine (ATC: ) it has been removed without replacement.

3) The azido group increases the lipophilic nature of AZT, allowing it to cross infected cell membranes easily by diffusion and thereby also to cross the blood–brain barrier.



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