autophosphorylation in a sentence
1) The significance of autophosphorylation is, however, entirely unclear.
2) In either event, dimerization results in the receptor's activation by autophosphorylation.
3) In vitro analyses revealed that Ajuba induces the autophosphorylation and consequent activation of AURKA.
4) Detection is followed by autophosphorylation of ComD, which in turn, phosphorylates ComE.
autophosphorylation example sentences
5) Photoexcitation of the LOV domain results in receptor autophosphorylation and an initiation of phototropin signaling.6) Small-molecule inhibitors of protein kinases generally prevent either phosphorylation of proteins substrates or autophosphorylation of the kinase itself.
7) In this scheme receptor activation results in autophosphorylation, creating a binding site for Grb2, as described previously.
8) ARQ197 is a non-ATP competitive c-MET autophosphorylation inhibitor with a high selectivity for the unphosphorylated conformation of the kinase.
9) The five tyrosine autophosphorylation sites in the catalytic core of FGFR1 are phosphorylated by a precisely controlled and ordered reaction.
10) The interaction between the cytoplasmic domains stimulates the autophosphorylation of tyrosines within the domains of the RTKs, causing conformational changes.
11) The FGFR1 signaling is achieved by receptor conformational changes upon ligand binding, leading to dimerization and subsequent activation by autophosphorylation of TK intracellular domains.
12) After ligand binding and autophosphorylation, such kinases may act as nucleation sites for the construction of ephemeral signaling complexes that contain many proteins.
13) Giese, K.P., N.B. Fedorov, R.K. Filipkowski, and A.J. Silva, autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning.
14) This change results in the autophosphorylation of the tyrosine residue located on the internal ß-subunit of the receptor, thereby activating the receptor's kinase activity.
example sentences with autophosphorylation
15) This insulin signal transduction pathway is composed of trigger mechanisms (e.g., autophosphorylation mechanisms) that serve as signals throughout the cell.16) When activated, these receptors undergo autophosphorylation on specific tyrosine residues, providing docking sites that bind to PLC- u0026ggr; and result in its activation.
17) The activation of the receptor by an external stimulus causes autophosphorylation in the histidine kinase, CheA, at a single highly conserved histidine residue.
18) The interaction between the SRK and SCR/SP11 proteins results in autophosphorylation of the intracellular kinase domain of SRK, and a signal is transmitted into the cell of the stigma.
19) PKR is potentially serine/threonine and tyrosine phosphorylated on 105 different sites (54 Ser, 33 Thr and 18 Tyr), including 15 suspected autophosphorylation sites.
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