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autocrine in a sentence


1) autocrine purinergic signalling is an important checkpoint in the activation of white blood cells.

2) The potential autocrine grown effects of gastrin in colorectal cancer have previously been studied using cell lines.

3) Therefore a potential growth stimulatory autocrine cycle may exist to explain the aggressive nature of these cancers.

4) The release of ATP and an autocrine feedback through P2RY2 and A3 receptors are signal amplifiers.



autocrine example sentences

5) SHH can signal in an autocrine fashion, affecting the cells in which it is produced.

6) This is contingent upon TGF-β autocrine signaling in a positive feedback loop with p38 and ERK.

7) The goal of the autocrine process is to fine-tune your milk production to meet baby's actual needs.

8) Some cells that secrete TGF-β also have receptors for TGF-β. This is known as autocrine signalling.

9) GnRH and the GnRH receptor are produced locally by immune cells, suggesting an autocrine role for GnRH.

10) It has been suggested that there is an autocrine mode of regulation by CSF1 in this cancer cell type.

11) It has been shown that autocrine TGF-β signaling is a compensatory result of mechanical stress in vitro in endothelial cells.

12) TNF-α acts as an autocrine stimulus by increasing the expression of both p47phox and p67phox transcripts.

13) Sometimes autocrine cells can target cells close by if they are the same type of cell as the emitting cell.

14) In Wnt signaling, these proteins act as ligands to activate the different Wnt pathways via paracrine and autocrine routes.



example sentences with autocrine

15) Estrogen can be released by the ovary and function as a hormone or act locally via paracrine or autocrine signaling.

16) Increased ET-1 production by the epithelium could also have an autocrine role, by promoting proliferation of type II pneumocytes.

17) DHT can act in an autocrine fashion on the stromal cells or in paracrine fashion by diffusing into nearby epithelial cells.

18) The hormone acts in endocrine, autocrine, and paracrine manner through the prolactin receptor and a large number of cytokine receptors.

19) The T cell is then stimulated to produce autocrines, resulting in the proliferation or differentiation to effector or memory T cells.

20) This can result from changes in presynaptic calcium as well as feedback onto presynaptic receptors, i.e. a form of autocrine signaling.

21) The model failed if the number of bins fell below about 20 for the autocrine signal IL-1, showing that "the IL-1 circuit must be analog.

22) Typically, they act in an autocrine and paracrine manner on their specific cell membrane receptor and mount an effective reparative response to any attack to biophysical integrity.

23) Together, the observations outlined above raise the possibility that gastrin might be acting as an autocrine growth factor in some colorectal cancers.

24) Both IL-1 and TNF participate in autocrine growth factors, increases cellular responsiveness to growth factors, and induces signaling pathways that lead to proliferation.

25) Under autocrine control, the breast responds to baby's demand by adjusting the speed of milk production upward or downward according to the amount of milk removed.

26) The term myokine refers to cytokines and other peptides that are produced, expressed, and released by muscle fibers and exert either autocrine, paracrine or endocrine effects.

27) Jiang X, Lopez A, Holyoake T, Eaves A u0026 Eaves C. autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia.

28) If an autocrine loops exists, then both the ligand (Wz) and receptor (Fzd) should be simultaneously expressed in myeloma cells and growth of tumour cells should be inhibited upon addition of SFRP1.

29) Methylation of soluble Wnt antagonists would be important in the pathogenesis of multiple myeloma if Wnt signaling was regulated by an autocrine loop by Wnt and Fz.



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