autoantigen in a sentence
1) Th1 overactivation against autoantigens will cause Type4 delayed-type hypersensitivity.
2) Th2 overactivation against autoantigen will cause Type1 IgE-mediated allergy and hypersensitivity.
3) Th17 overactivation against autoantigen will cause type 3 immune complex and complement-mediated hypersensitivity.
4) Its 31,000 children in 11 adults increase autoantigens in both therapeutic concentrations and other symptoms.
autoantigen example sentences
5) Knowledge of binding epitopes on the autoantigen is necessary to understand the subsequent pathologic events.6) Overactivation of THαβ against autoantigen will cause type 2 antibody-dependent cytotoxic hypersensitivity.
7) Inducing tolerance to the host autoantigen in this way may also be the most stable factor.
8) Epidermal transglutaminase (eTG) is related to tTG and is the autoantigen of DH.
9) Studies on mice models suggest that estrogen deficiency stimulates presentation of autoantigens, inducing Sjogren's syndrome-like symptoms.
10) In a nonobese diabetic mouse model, peripherin has been found as a known autoantigen (See antigen).
11) Autoimmunity possibly results by the extended exposure to nuclear and intracellular autoantigens derived from late apoptotic and secondary necrotic cells.
12) David Jones reviewed autoantigens and trigger factors in PBC and presented data on novel animal models that may elucidate pathogenesis.
13) Diego Vergani reviewed current understanding of autoantigens in autoimmune hepatitis and showed how defective regulatory T cell function contributes to disease development.
14) This can be compared with an autoantigen, in which a person develops antibodies to one or more of their own proteins.
example sentences with autoantigen
15) The structural features of the B-CLL BCRs resemble those of mAb's reactive with carbohydrate determinants of bacterial capsules or viral coats and with certain autoantigens.16) B and T cell tolerance for apoptotic cells is abrogated, and the lymphocytes get activated by these autoantigens; inflammation and the production of autoantibodies by plasma cells is initiated.
17) Necrotic cells release nuclear fragments as potential autoantigens, as well as internal danger signals, inducing maturation of dendritic cells (DCs), since they have lost their membranes' integrity.
18) The use of the word alloantigen actually masks the fact that HLA are infrequently autoantigens in the donor, and therefore their function is not as antigens, but something else.
19) Sharma, A., Isenberg, D., and Diamond, B. Studies of human polyclonal and monoclonal antibodies binding to lupus autoantigens and crossreactive antigens.
20) In 1994 GluR3 was shown to act as an autoantigen in Rasmussen's encephalitis, leading to speculation that autoimmune activity might underlie the condition.
21) Injections with a vaccine containing GAD65, an autoantigen involved in type 1 diabetes, has in clinical trials delayed the destruction of beta cells when treated within six months of diagnosis.
22) GAD, a presynaptic autoantigen, is generally thought to play a key role in the condition, but exact details of the way that autoantibodies affect SPS patients are not known.
23) Extractable nuclear antigens (ENA) are a group of autoantigens that were originally identified as antibody targets in people with autoimmune disorders.
24) In normal physiology, lymphocytes that recognise human proteins (autoantigens) either undergo programmed cell death (apoptosis) or become non-functional.
25) In normal individuals, the immune system produces antibodies to foreign proteins (antigens) but not to human proteins (autoantigens).
26) Thus although polymyositis is more or less tissue specific in presentation, it may be included in this group because the autoantigens are often ubiquitous t-RNA synthetases.
27) In 2008, mucosal administration of α-fodrin, an autoantigen in Sjögren's syndrome, was shown to inhibit the progression of the disorder in mice effectively.
28) The team is also working on the post-translational modification of autoantigens to use as new vaccin
29) The autoantigens believed to cause the autoreactivity are the alpha and beta subunits of the H+/K+-ATPase.
30) A number of diseases in humans have a proven association with genetic mutations of glutamate receptor genes, or autoantigen/antibody interactions with glutamate receptors or their genes.
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